FDA drug information available at new site

I am unveiling my latest project: a drug information site called What's the dose.com

You get access to about 10,000 package inserts and 46,000 pieces of drug information.  I integrate an FDA database and a repository of thousands of drug package inserts.

Google is such an inadequate resource for quickly finding drug information that I hope my new site provides answers more quickly and accurately.

Pharmacies

I haven't ranted here in three years, so I think I'm entitled to rant a little today.

A pharmacist at Walgreens called for a clarification on "CW," evidently not everyone knows this means "chest wall."  He left a number, I called back.

I get this long schpiel on how flu shots are available at your local Walgreens, and why not come on down to get your flu shot, and by the way, we also sell alcohol and tobacco for your convenience.  Ok so maybe I made that last part up.

Abstract roundup 7-31-11

Podcast file: 

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Six reports tonight:

7-29-11 abstracts (only 3!)

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19: Low-dose diethylstilbestrol for the treatment of advanced prostate cancer.
Urol Oncol. 2011 Jul 25; [Epub ahead of print]

7-28-11 abstracts

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20: Conservative Versus Liberal Red Cell Transfusion in Acute Myocardial Infarction (the CRIT Randomized Pilot Study).
Am J Cardiol. 2011 Jul 24; [Epub ahead of print]

Interesting MEDLINE abstracts from 7/27/11

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7: Impact of maternal supplementation with probiotics during pregnancy on atopic eczema in childhood - a meta-analysis.
Br J Nutr. 2011 Jul 26;:1-6 [Epub ahead of print]

Round 3: Nephrology

I'm just happy Andrew Pollack decided to go after nephrologists (and not oncologists) with his latest NYT:

Lawsuit Says Drugs Were Wasted to Buoy Profit

The cardiologists and oncologists are his usual favorite whipping boys, not today!

Fascinating article.

Stem cell transplant way more effective than cytoxan for scleroderma

I don't follow scleroderma, but the numbers reported here are pretty impressive.  Stem cell transplant was far more effective than chemotherapy for scleroderma treatment.  I'm sure not every case is a candidate for transplant, but this article, reported this week in Lancet, bears a look, I think.

Autologous non-myeloablative haemopoietic stem-cell transplantation compared with pulse cyclophosphamide once per month for systemic sclerosis (ASSIST): an open-label, randomised phase 2 trial.

http://www.ncbi.nlm.nih.gov/pubmed/21778673

Vitamin K derivative and hip fractures

Here's a publication from a foreign journal that might even be more interesting than the UCLA article on bazedoxifene. 

Menatetrenone is Vitamin K-2.  Somehow, Vitamin K is supposed to affect bone density, but I don't think anyone understands how.  The Japanese have been long studying this substance, and the "Kurume Med Journal" this week put out a report on the stuff.  I have to admit, I don't have a subscription.

Evidently the stuff is available as a medication in Japan, though not in US.

Bazedoxifene, osteoporosis, and journals

Sustained efficacy and safety of bazedoxifene in preventing fractures in postmenopausal women with osteoporosis: results of a 5-year, randomized, placebo-controlled study.

 

Article was published in the journal Osteoporosis International, not NEJM.  Epub was from July 21, 2011.  The researchers, located here in Los Angeles, found that SERM bazedoxifene was successful in protecting against fractures in osteoporotic women.

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